Table 1 Comparison of baseline data before and after propensity score matching
Categories | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
No-HFNC | HFNC | SMD | No-HFNC | HFNC | SMD | |
Number of patients | 9914 | 510 | 510 | 510 | ||
Age | 65.71 (15.22) | 65.97 (15.43) | 0.017 | 64.60 (16.59) | 65.97 (15.43) | 0.086 |
Gender | ||||||
Female | 3773 (38.1) | 219 (42.9) | 0.1 | 219 (42.9) | 219 (42.9) | < 0.001 |
Male | 6141 (61.9) | 291 (57.1) | 291 (57.1) | 291 (57.1) | ||
Race | ||||||
Black | 616 (6.2) | 18 (3.5) | 0.143 | 8 (1.6) | 18 (3.5) | 0.132 |
White | 6619 (66.8) | 344 (67.5) | 343 (67.3) | 344 (67.5) | ||
Other | 950 (9.6) | 44 (8.6) | 51 (10.0) | 44 (8.6) | ||
Unknow | 1729 (17.4) | 104 (20.4) | 108 (21.2) | 104 (20.4) | ||
First care unit | ||||||
Surgical ICU | 1451 (14.6) | 96 (18.8) | 0.264 | 85 (16.7) | 96 (18.8) | 0.085 |
Medical ICU | 1808 (18.2) | 102 (20.0) | 116 (22.7) | 102 (20.0) | ||
CCU | 4153 (41.9) | 151 (29.6) | 156 (30.6) | 151 (29.6) | ||
Other | 2502 (25.2) | 161 (31.6) | 153 (30.0) | 161 (31.6) | ||
BMI | 29.63 (7.74) | 29.51 (8.63) | 0.015 | 29.77 (8.06) | 29.51 (8.63) | 0.032 |
SOFA | 3.00 [2.00, 5.00] | 3.00 [2.00, 5.00] | 0.045 | 3.00 [2.00, 5.00] | 3.00 [2.00, 5.00] | 0.092 |
Comorbidities | ||||||
Cerebrovascular disease | 1496 (15.1) | 58 (11.4) | 0.11 | 87 (17.1) | 58 (11.4) | 0.163 |
Dementia | 233 (2.4) | 16 (3.1) | 0.048 | 15 (2.9) | 16 (3.1) | 0.011 |
Rheumatic disease | 332 (3.3) | 13 (2.5) | 0.047 | 20 (3.9) | 13 (2.5) | 0.078 |
Congestive heart failure | 2915 (29.4) | 180 (35.3) | 0.126 | 142 (27.8) | 180 (35.3) | 0.161 |
Chronic pulmonary disease | 2777 (28.0) | 195 (38.2) | 0.219 | 147 (28.8) | 195 (38.2) | 0.2 |
Diabetes with cc | 756 (7.6) | 70 (13.7) | 0.199 | 29 (5.7) | 70 (13.7) | 0.274 |
Diabetes without cc | 2452 (24.7) | 103 (20.2) | 0.109 | 135 (26.5) | 103 (20.2) | 0.149 |
Renal disease | 1835 (18.5) | 102 (20.0) | 0.038 | 89 (17.5) | 102 (20.0) | 0.065 |
Mild liver disease | 1469 (14.8) | 76 (14.9) | 0.002 | 81 (15.9) | 76 (14.9) | 0.027 |
Severe liver disease | 678 (6.8) | 42 (8.2) | 0.053 | 39 (7.6) | 42 (8.2) | 0.022 |
Malignant cancer | 1045 (10.5) | 73 (14.3) | 0.115 | 56 (11.0) | 73 (14.3) | 0.1 |
Treatment | ||||||
Antibiotic_6h | 6049 (61.0) | 335 (65.7) | 0.097 | 315 (61.8) | 335 (65.7) | 0.082 |
Antibiotic_24h | 7965 (80.3) | 424 (83.1) | 0.072 | 435 (85.3) | 424 (83.1) | 0.059 |
CRRT_24h | 347 (3.5) | 22 (4.3) | 0.042 | 16 (3.1) | 22 (4.3) | 0.062 |
Vasoactive_24h | 5954 (60.1) | 247 (48.4) | 0.235 | 315 (61.8) | 247 (48.4) | 0.271 |
Ventilation_24h | 4987 (50.3) | 195 (38.2) | 0.245 | 227 (44.5) | 195 (38.2) | 0.128 |
Vital signs | ||||||
Heart rate (beats/min) | 87.10 (15.53) | 89.04 (16.56) | 0.121 | 89.25 (16.46) | 89.04 (16.56) | 0.013 |
Respiratory rate (bpm) | 19.97 (4.18) | 21.24 (4.17) | 0.305 | 21.09 (4.52) | 21.24 (4.17) | 0.033 |
Temperature (℃) | 36.99 (0.68) | 37.01 (0.54) | 0.034 | 36.98 (0.72) | 37.01 (0.54) | 0.045 |
Mean arterial pressure (mm Hg) | 75.77 (9.29) | 76.44 (9.59) | 0.072 | 75.62 (9.75) | 76.44 (9.59) | 0.085 |
Laboratory test | ||||||
WBC (109/L) | 12.95 (8.52) | 13.76 (9.38) | 0.09 | 13.52 (10.45) | 13.76 (9.38) | 0.024 |
Hemoglobin (g/dl) | 10.13 (1.60) | 9.85 (1.89) | 0.159 | 10.21 (1.80) | 9.85 (1.89) | 0.195 |
Platelet (109/L) | 175.00 (96.53) | 179.51 (98.52) | 0.046 | 178.31 (97.55) | 179.51 (98.52) | 0.012 |
PH | 7.37 (0.07) | 7.39 (0.07) | 0.195 | 7.36 (0.08) | 7.39 (0.07) | 0.295 |
Lactate (mmol/L) | 2.17 (1.82) | 1.97 (1.61) | 0.119 | 2.40 (2.18) | 1.97 (1.61) | 0.224 |
PaO2/FiO2 (mm Hg) | 156.74 (68.11) | 104.87 (49.37) | 0.872 | 103.65 (49.83) | 104.87 (49.37) | 0.025 |