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  1. Physiotherapy is a cornerstone of cystic fibrosis (CF) management, yet the Australian CF Data Registry (ACFDR) currently does not record physiotherapy-related data. This study aimed to gather opinions from lea...

    Authors: Angela Potter, Bhavita Pancholi, Lahni Smith and Carol Maher

    Citation: BMC Pulmonary Medicine 2021 21:298

    Content type: Research

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  2. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an important event in the course of chronic obstructive pulmonary disease that negatively affects patients’ quality of life and leads to ...

    Authors: Lingling Tang, Suofang Shi, Bohan Wang, Li Liu, Ying Yang, Xianhong Sun, Zhenhua Ni and Xiongbiao Wang

    Citation: BMC Pulmonary Medicine 2021 21:296

    Content type: Research

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  3. In the local setting, asthma control is assessed by symptoms and signs elicited by clinicians because of the limited availability of spirometry. Hence, we intended to develop a patient reported outcome measure...

    Authors: Yalini Guruparan, Thiyahiny S. Navaratinaraja, Gowry Selvaratnam, Nalika Gunawardena and Shalini Sri Ranganathan

    Citation: BMC Pulmonary Medicine 2021 21:295

    Content type: Research

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  4. Acute exacerbation (AE) is the most lethal postoperative complication in idiopathic pulmonary fibrosis (IPF); however, prediction before surgery is difficult. We investigated the role of 18F-fluorodeoxyglucose po...

    Authors: Hee-Young Yoon, Suk Hyun Lee, Sejin Ha, Jin-Sook Ryu and Jin Woo Song

    Citation: BMC Pulmonary Medicine 2021 21:294

    Content type: Research

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  5. Re-expansion pulmonary edema is an uncommon complication following drainage of a pneumothorax or pleural effusion. While pneumothorax is noted to complicate COVID-19 patients, no case of COVID-19 developing re...

    Authors: Kosaku Komiya, Ryosuke Hamanaka, Hisayuki Shuto, Hiroki Yoshikawa, Atsushi Yokoyama, Kazufumi Hiramatsu and Jun-ichi Kadota

    Citation: BMC Pulmonary Medicine 2021 21:293

    Content type: Case report

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  6. Asthma is a chronic inflammatory disorder of the airways involving many different factors. This study aimed to screen for the critical genes using DNA methylation/CpGs and miRNAs involved in childhood atopic a...

    Authors: Rui Chen, Li-Zhen Piao, Ling Liu and Xiao-Fei Zhang

    Citation: BMC Pulmonary Medicine 2021 21:292

    Content type: Research article

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  7. In recent years, the application of immunotherapy combined with chemotherapy in the first-line lung cancer has showed significant benefit in improving long-term survival. Immunotherapy also has risks of immune...

    Authors: Yu Feng, Cuncun Chen, Liming Zhao, Xuyou Zhu, Xiaoping Zhu and Qiang Li

    Citation: BMC Pulmonary Medicine 2021 21:291

    Content type: Case report

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  8. Chronic cough is characterized by cough as the only or main symptom, with a duration of more than 8 weeks and no obvious abnormality in chest X-ray examination. Its etiology is complex, including respiratory d...

    Authors: Jiaofei Cao, Yue Hu, Shaojun Jin, Fei Chen, Li Li and Huaqiong Huang

    Citation: BMC Pulmonary Medicine 2021 21:290

    Content type: Case report

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  9. Refractory dyspnea or breathlessness is a common symptom in patients with advanced chronic obstructive pulmonary disease (COPD), with a high negative impact on quality of life (QoL). Low dosed opioids have bee...

    Authors: Marlies van Dijk, Kris J. M. Mooren, Jan-Willem K. van den Berg, Wendy J. C. van Beurden-Moeskops, Roxane Heller-Baan, Sander M. de Hosson, Wai Yee Lam-Wong, Liesbeth Peters, Karin Pool and Huib A. M. Kerstjens

    Citation: BMC Pulmonary Medicine 2021 21:289

    Content type: Study protocol

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  10. Diffuse alveolar hemorrhage (DAH) is a syndrome resulting from bleeding in the microcirculation of the lung, with a poor prognosis. The study aim was to identify prognostic factors of DAH, especially bronchoal...

    Authors: Kensuke Kanaoka, Seigo Minami, Shoichi Ihara and Kiyoshi Komuta

    Citation: BMC Pulmonary Medicine 2021 21:288

    Content type: Research

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  11. Lung adenocarcinoma (LUAD) is the most common histological subtype of primary lung cancer. To identify the biomarker of diagnosis for LUAD is of great significance. Long non-coding RNAs (lncRNAs) were previous...

    Authors: Wen Huang, Xinxing Wang, Fubing Wu and Fanggui Xu

    Citation: BMC Pulmonary Medicine 2021 21:287

    Content type: Research

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  12. In the treatment of lung cancer, the presence or absence of mediastinal lymph node involvement has a significant bearing on the indication for surgery. In addition, if a tumor is found in the trachea during pr...

    Authors: Yutaka Takahara, Kouichi Yamamura, Nozomu Motono, Taku Oikawa, Hidetaka Uramoto and Shiro Mizuno

    Citation: BMC Pulmonary Medicine 2021 21:286

    Content type: Case report

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  13. Oxygen therapy is routinely administered to mechanically ventilated patients. However, there remains uncertainty about the optimal oxygen titration target in patients with the acute respiratory distress syndro...

    Authors: Andrew J. Boyle, David N. Holmes, Jonathan Hackett, Susanna Gilliland, Michael McCloskey, Cecilia M. O’Kane, Paul Young, Stefania Di Gangi and Daniel F. McAuley

    Citation: BMC Pulmonary Medicine 2021 21:285

    Content type: Research article

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  14. Treatment for non-small cell lung cancer (NSCLC) has greatly improved in recent years. However, noninvasive early screening for carcinogenesis and progression unclear. The aim of this study was to explore the ...

    Authors: Yingyi Wang, Na Zhou, Rui Zhu, Xiaoyuan Li, Zhao Sun, Yang Gao, Wei Liu, Changting Meng, Yuping Ge, Chunmei Bai, Taisheng Li and Hongsheng Liu

    Citation: BMC Pulmonary Medicine 2021 21:282

    Content type: Research

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  15. There is a lack of clinical-radiological predictive models for the small (≤ 20 mm) solitary pulmonary nodules (SPNs). We aim to establish a clinical-radiological predictive model for differentiating malignant ...

    Authors: Hai-Cheng Zhao, Qing-Song Xu, Yi-Bing Shi and Xi-Juan Ma

    Citation: BMC Pulmonary Medicine 2021 21:281

    Content type: Research

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  16. Identifying or prioritizing genes for chronic obstructive pulmonary disease (COPD), one type of complex disease, is particularly important for its prevention and treatment.

    Authors: Wan Li, Yihua Zhang, Yahui Wang, Zherou Rong, Chenyu Liu, Hui Miao, Hongwei Chen, Yuehan He, Weiming He and Lina Chen

    Citation: BMC Pulmonary Medicine 2021 21:280

    Content type: Research

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  17. There are various reasons for delayed positive nasopharyngeal PCR tests for coronavirus disease 2019 (COVID19) in not only asymptomatic but also severely diseased patients. The pathophysiological attributes ar...

    Authors: Lei Zhang, Syam P. Vunnamadala, Shigeo Yagi, Riffat Meraj and Michele Carbone

    Citation: BMC Pulmonary Medicine 2021 21:278

    Content type: Case report

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  18. LncRNA DLGAP1-AS2 plays an oncogenic role in glioma, while its role in other cancers is unknown. This study aimed to study the role of DLGAP1-AS2 in non-small cell lung cancer (NSCLC).

    Authors: Lu Wang, Lei Tang, Tengfei Ge, Feng Zhu, Dan Liu, Hua Guo, Peng Qian and Ning Xu

    Citation: BMC Pulmonary Medicine 2021 21:277

    Content type: Research article

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  19. How cigarette smoke (CS) and chronic obstructive pulmonary disease (COPD) affect severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and severity is controversial. We investigated the effects...

    Authors: M. Tomchaney, M. Contoli, J. Mayo, S. Baraldo, S. Li, C. R. Cabel, D. A. Bull, S. Lick, J. Malo, S. Knoper, S. S. Kim, J. Tram, J. Rojas-Quintero, M. Kraft, J. G. Ledford, Y. Tesfaigzi…

    Citation: BMC Pulmonary Medicine 2021 21:275

    Content type: Research

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  20. Transbronchial lung cryobiopsy is a safe technique increasingly used in the study of lung diseases. Until now, only a case of pneumatocele was described but this interesting condition is probably underestimate...

    Authors: Roberto Piro, Sofia Taddei, Matteo Fontana, Chiara Scelfo, Eleonora Casalini and Nicola Facciolongo

    Citation: BMC Pulmonary Medicine 2021 21:274

    Content type: Case report

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  21. Within the pathogenesis of the chronic obstructive pulmonary disease (COPD) there are interactions between different inflammatory mediators that are enhanced during an exacerbation. Arginase is present in bron...

    Authors: Marcel Jose Rodríguez-Guzmán, Germán Peces-Barba Romero, Sandra Pérez Rial, Cristina Serrano del Castillo, Miguel Ángel Palomero Rodríguez, Ignacio Mahillo-Fernandez and Felipe Villar-Álvarez

    Citation: BMC Pulmonary Medicine 2021 21:271

    Content type: Research article

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  22. Adult patients with cystic fibrosis (CF) experience daily physical symptoms and disabilities that can be challenging to address for health care teams.

    Authors: Sandra Dury, Jeanne-Marie Perotin, Bruno Ravoninjatovo, Catherine Llerena, Julien Ancel, Pauline Mulette, Muriel Griffon, Sophie Carré, Amélie Perrin, François Lebargy, Gaëtan Deslée and Claire Launois

    Citation: BMC Pulmonary Medicine 2021 21:270

    Content type: Research

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  23. Bronchiectasis is a major contributor to respiratory morbidity and healthcare utilization in children. Children with bronchiectasis exhibit low levels of physical activity (PA) and poor fundamental movement sk...

    Authors: Barbara Joschtel, Sjaan R. Gomersall, Sean Tweedy, Helen Petsky, Anne B. Chang and Stewart G. Trost

    Citation: BMC Pulmonary Medicine 2021 21:269

    Content type: Research

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  24. Curcumin, a derivative of the spice turmeric, has been adopted by Eastern medicine for centuries as an adjunct to treat several medical conditions (e.g., anorexia and arthritis) because of its well-established...

    Authors: Michele Quan, Abdullah Alismail, Noha Daher, Derrick Cleland, Sonia Chavan and Laren D. Tan

    Citation: BMC Pulmonary Medicine 2021 21:268

    Content type: Study protocol

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  25. The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairme...

    Authors: Álvaro Mingote, Andrea Albajar, Paulino García Benedito, Jessica Garcia-Suarez, Paolo Pelosi, Lorenzo Ball and Javier García-Fernández

    Citation: BMC Pulmonary Medicine 2021 21:267

    Content type: Research

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  26. Incorrect use of inhalers among asthma and COPD patients is very prevalent. Yet, no single intervention is considered standard of care. We aimed to conduct a COPD-specific investigation of active one-on-one co...

    Authors: Jin Sun Kim, Nader Hashweh, Hannah Li, Salik Choudhary, Sadashiv Santosh and Edward Charbek

    Citation: BMC Pulmonary Medicine 2021 21:266

    Content type: Research article

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  27. The objective of the present study is to describe the clinical, diagnostic, radiological and therapeutic aspects of osteoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if t...

    Authors: Napoleón González Saldaña, Mercedes Macías Parra, Luis Xochihua Díaz, Martin Palavicini Rueda, Ana Jocelyn Carmona Vargas, José Iván Castillo Bejarano, Quetzalli Veloz Corona, Hugo Juárez Olguín and Juan Luis Chavez Pacheco

    Citation: BMC Pulmonary Medicine 2021 21:265

    Content type: Research

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  28. Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by acute hypoxaemia, and few studies have reported the incidence of deep vein thrombosis (DVT) in direct ARDS caused by bacterial...

    Authors: Na Cui, Song Mi, Chunguo Jiang, Wanlu Sun, Wenping Mao, Liming Zhang and Xiaokai Feng

    Citation: BMC Pulmonary Medicine 2021 21:264

    Content type: Research

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  29. Kartagener syndrome is a subtype of primary ciliary dyskinesia that may exhibit various symptoms including neonatal respiratory distress and frequent infections of the lung, sinus and middle ear because of the...

    Authors: Lina Wang, Xin Zhao, Hang Liang, Li Zhang, Chunyan Li, Deli Li, Xiangfeng Meng, Fanzheng Meng and Mao Gao

    Citation: BMC Pulmonary Medicine 2021 21:263

    Content type: Case report

    Published on:

  30. While lung transplant (LTX) can be an effective therapy to provide the survival benefit in selected populations, post-transplant outcome in LTX recipients with bronchiectasis other than cystic fibrosis (CF) ha...

    Authors: Takashi Hirama, Fumiko Tomiyama, Hirotsugu Notsuda, Tatsuaki Watanabe, Yui Watanabe, Hisashi Oishi and Yoshinori Okada

    Citation: BMC Pulmonary Medicine 2021 21:261

    Content type: Research

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  31. The 6th World Symposium on Pulmonary Hypertension (Nice 2018) proposed a new definition of pre-capillary pulmonary hypertension (PH) as a condition with mean pulmonary artery pressure (mPAP) > 20 mmHg, pulmona...

    Authors: Keiko Yamamoto, Nobuhiro Tanabe, Yukiko Takahashi, Akira Naito, Ayumi Sekine, Rika Suda, Takayuki Jujo Sanada, Toshihiko Sugiura, Ayako Shigeta, Seiichiro Sakao and Koichiro Tatsumi

    Citation: BMC Pulmonary Medicine 2021 21:260

    Content type: Research

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  32. Tests to identify reversible airflow limitation are important in asthma diagnosis, but they are time-consuming and it may be difficult for patients to cooperate. We aimed to evaluate whether the combination of...

    Authors: Jiang-Hua Li, Rui Han, Yu-Bo Wang, Min Cheng, Heng-Yi Chen, Wen-Hui Lei, Li Li, Chen Gao, Na-Na Zhao, Nai-Fu Nie, Zhong-Yan Li, Guo-Qing Yin, Shuai Huang and Yong He

    Citation: BMC Pulmonary Medicine 2021 21:259

    Content type: Research article

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  33. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common presentation in emergency departments (ED) that can be fatal. This study aimed to develop a mortality risk assessment model for ...

    Authors: Lan Chen, Lijun Chen, Han Zheng, Sunying Wu and Saibin Wang

    Citation: BMC Pulmonary Medicine 2021 21:258

    Content type: Research

    Published on:

  34. We aim to analyze the risk factors for pneumothorax associated with computed tomography (CT)-guided percutaneous core needle biopsy (PCNB) of the lung. Whether the lung function characteristics are related to ...

    Authors: Chunhai Li, Dexiang Wang, Fengxia Yang, Yang Song, Xuejuan Yu, Bo Liu, Haipeng Jia and Wei Zhou

    Citation: BMC Pulmonary Medicine 2021 21:257

    Content type: Research

    Published on:

  35. Functional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative information about lung structure and function. FRI has proven its value in pulmo...

    Authors: Eline Lauwers, Annemiek Snoeckx, Kris Ides, Kim Van Hoorenbeeck, Maarten Lanclus, Wilfried De Backer, Jan De Backer and Stijn Verhulst

    Citation: BMC Pulmonary Medicine 2021 21:256

    Content type: Research article

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  36. Research on health-related quality of life (HRQL) has become increasingly important in recent decades. However, the impact of both living conditions and the level of autonomy impairments on HRQL in COPD patien...

    Authors: Sarah Bettina Schwarz, Tim Mathes, Daniel Sebastian Majorski, Maximilian Wollsching-Strobel, Doreen Kroppen, Friederike Sophie Magnet and Wolfram Windisch

    Citation: BMC Pulmonary Medicine 2021 21:255

    Content type: Research

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  37. Aspiration pneumonitis is an inflammatory disease of the lungs which is difficult to diagnose accurately. Large-volume aspiration of oropharyngeal or gastric contents is essential for the development of aspira...

    Authors: Jiayu Cao, Wei Liu, Li Wang, Yujuan Yang, Yu Zhang and Xicheng Song

    Citation: BMC Pulmonary Medicine 2021 21:254

    Content type: Case report

    Published on:

  38. Adherence to chronic obstructive pulmonary disease (COPD) maintenance medication is important for managing symptoms and exacerbation risk, and is associated with reduced mortality, hospitalizations, and costs....

    Authors: David Slade, Riju Ray, Chad Moretz, Guillaume Germain, François Laliberté, Qin Shen, Mei Sheng Duh, Malena Mahendran and Beth Hahn

    Citation: BMC Pulmonary Medicine 2021 21:253

    Content type: Research article

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  39. This study aimed to determine the effects of emodin on the viability, proliferation and apoptosis of human pulmonary artery smooth muscle cells (PASMCs) under hypoxia and to explore the underling molecular mec...

    Authors: Li Yi, JunFang Liu, Ming Deng, Huihua Zuo and Mingyan Li

    Citation: BMC Pulmonary Medicine 2021 21:252

    Content type: Research

    Published on:

  40. Systemic sclerosis (SSc) is a rare disease, and the presence of pulmonary hypertension can be a determining factor in prognosis. The aim of this study was to evaluate the diagnosis, profile, and prognosis of s...

    Authors: Verônica Silva Vilela, Marcio Macri Dias, Ângelo Antunes Salgado, Bruno Rangel Antunes da Silva, Agnaldo José Lopes, Elizabeth Jauhar Cardoso Bessa, Leonardo Palermo Bruno, Cláudia Henrique da Costa, Roger Abramino Levy and Rogério Rufino

    Citation: BMC Pulmonary Medicine 2021 21:251

    Content type: Research article

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  41. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of patients with COPD. Guidelines have recommended systemic glucocorticoid as a regular treatment. Rec...

    Authors: Qiu-Yu Li, Zhuo-Yu An, Zi-Han Pan and Rui-Ying Qi

    Citation: BMC Pulmonary Medicine 2021 21:250

    Content type: Study protocol

    Published on:

  42. Treatment for interstitial lung disease (ILD) patients with acute respiratory failure (ARF) is challenging, and literature to guide such treatment is scarce. The reported in-hospital mortality rates of ILD pat...

    Authors: Johanna P. van Gemert, Inge A. H. van den Berk, Esther J. Nossent, Leo M. A. Heunks, Rene E. Jonkers, Alexander P. Vlaar and Peter I. Bonta

    Citation: BMC Pulmonary Medicine 2021 21:249

    Content type: Research article

    Published on:

  43. Authors: Benoît Misset, Eric Hoste, Anne Françoise Donneau, David Grimaldi, Geert Meyfroidt, Michel Moutschen, Veerle Compernolle, André Gothot, Daniel Desmecht, Mutien Garigliany, Tome Najdovski and Pierre François Laterre

    Citation: BMC Pulmonary Medicine 2021 21:248

    Content type: Correction

    Published on:

    The original article was published in BMC Pulmonary Medicine 2020 20:317

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