Clinicopathological features | Cases | TLS(CT)* | TLS(IM)* | TLS* | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Agg | FOL-I | FOL-II | Agg | FOL-I | FOL-II | (Overall) | ||||||||||||||||
Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | ||
Gender | 0.45 | 0.133 | 0.742 | 0.952 | 0.497 | 0.958 | 0.834 | |||||||||||||||
Female | 84 | 51 | 33 | 59 | 25 | 70 | 14 | 55 | 29 | 51 | 33 | 75 | 9 | 60 | 24 | |||||||
Male | 67 | 44 | 23 | 50 | 17 | 57 | 10 | 40 | 27 | 37 | 30 | 60 | 7 | 46 | 21 | |||||||
Ages | 0.983 | 0.308 | 0.221 | 0.42 | 0.811 | 0.862 | 0.945 | |||||||||||||||
<60 | 63 | 39 | 24 | 48 | 15 | 52 | 11 | 40 | 23 | 36 | 27 | 56 | 7 | 44 | 19 | |||||||
≥ 60 | 88 | 56 | 32 | 61 | 27 | 75 | 13 | 55 | 33 | 52 | 36 | 79 | 9 | 62 | 26 | |||||||
Smoking status | 0.272 | 0.037 | 0.974 | 0.923 | 0.053 | 0.05 | 0.006 | |||||||||||||||
Non-smoking | 87 | 60 | 27 | 69 | 18 | 75 | 12 | 53 | 34 | 54 | 33 | 81 | 6 | 67 | 20 | |||||||
Smoking | 51 | 25 | 26 | 29 | 22 | 39 | 12 | 30 | 21 | 23 | 28 | 42 | 9 | 27 | 24 | |||||||
Differentiation | 0.04 | 0.119 | 0.879 | 0.642 | 0.658 | 0.232 | 0.466 | |||||||||||||||
Higher differentiation | 99 | 60 | 39 | 68 | 31 | 81 | 18 | 62 | 37 | 58 | 41 | 86 | 13 | 68 | 31 | |||||||
Middle -low differentiation | 35 | 24 | 11 | 28 | 7 | 31 | 4 | 21 | 14 | 22 | 13 | 33 | 2 | 26 | 9 | |||||||
Histological type | 0.539 | 0.672 | 0.439 | 0.543 | 0.583 | 0.949 | 0.974 | |||||||||||||||
Adenocarcinoma | 141 | 88 | 53 | 101 | 40 | 117 | 24 | 89 | 52 | 83 | 58 | 126 | 15 | 99 | 42 | |||||||
Non-adenocarcinoma | 10 | 7 | 3 | 8 | 2 | 10 | 0 | 6 | 4 | 5 | 5 | 9 | 1 | 7 | 3 | |||||||
Metastasis status | 0 | 0.001 | 0.139 | 0 | 0.154 | 0.031 | 0 | |||||||||||||||
Non-metastasis | 56 | 24 | 32 | 30 | 26 | 39 | 17 | 25 | 31 | 28 | 28 | 46 | 10 | 28 | 28 | |||||||
Metastasis | 92 | 68 | 24 | 76 | 16 | 85 | 7 | 67 | 25 | 57 | 35 | 86 | 6 | 75 | 17 | |||||||
UICC stage | 0 | 0.008 | 0.13 | 0 | 0.028 | 0.119 | 0 | |||||||||||||||
I | 47 | 18 | 29 | 23 | 24 | 30 | 17 | 18 | 29 | 22 | 25 | 38 | 9 | 20 | 27 | |||||||
II | 14 | 8 | 6 | 8 | 6 | 13 | 1 | 10 | 4 | 10 | 4 | 13 | 1 | 11 | 3 | |||||||
III | 57 | 37 | 20 | 45 | 12 | 53 | 4 | 37 | 20 | 31 | 26 | 52 | 5 | 43 | 14 | |||||||
IV | 32 | 31 | 1 | 32 | 0 | 30 | 2 | 29 | 3 | 24 | 9 | 31 | 1 | 31 | 1 | |||||||
CD8 | 0.001 | 0.025 | 0.089 | 0.175 | 0.088 | 0.31 | 0.013 | |||||||||||||||
Negative | 59 | 45 | 14 | 51 | 8 | 53 | 6 | 42 | 17 | 40 | 19 | 55 | 4 | 48 | 11 | |||||||
Positive | 84 | 45 | 39 | 54 | 30 | 67 | 17 | 49 | 35 | 45 | 39 | 74 | 10 | 53 | 31 |