Table 1 Demographic and clinical characteristics of the study population and SF-36 summary scores, n=4398
| Â | n (%) | Mental Component Summary (MCS) scorea | Physical Component Summary (PCS) scorea |
|---|---|---|---|
mean (SD) | mean (SD) | ||
Age, years | |||
 <50 | 1010 (22.96) | 48.15 (11.57) | 35.65 (10.05) |
 50-65 | 2355 (53.55) | 51.27 (10.64) | 36.30 (9.83) |
 >65 | 1033 (23.49) | 53.97 (9.37) | 37.10 (9.29) |
Sex | |||
 Female | 1996 (45.38) | 51.58 (10.52) | 36.38 (9.91) |
 Male | 2402 (54.62) | 50.87 (10.95) | 36.31 (9.64) |
mMRCb | |||
 0 | 404 (9.19) | 54.25 (8.36) | 45.48 (9.27) |
 1 | 986 (22.42) | 53.63 (8.96) | 41.87 (8.75) |
 2 | 826 (18.78) | 51.92 (10.42) | 36.78 (8.29) |
 3 | 950 (21.60) | 50.94 (10.89) | 33.64 (8.06) |
 4 | 1232 (28.01) | 47.90 (11.99) | 30.63 (8.05) |
Frequency of exacerbations in the past year | |||
 0 | 1001 (22.76) | 53.99 (9.07) | 40.32 (9.56) |
 1 | 915 (20.80) | 52.89 (9.89) | 38.39 (9.48) |
 2 or more | 2482 (56.43) | 49.43 (11.35) | 33.97 (9.25) |
Regular use of oxygen in the past year | |||
 No | 2193 (49.86) | 51.67 (10.46) | 39.33 (9.77) |
 Yes | 2205 (50.14) | 50.71 (11.04) | 33.36 (8.80) |
Daily productive cough for at least 3 months each year over the past 2 years | |||
 No | 2462 (55.98) | 52.35 (10.20) | 37.96 (9.76) |
 Yes | 1936 (44.02) | 49.72 (11.27) | 34.27 (9.38) |
Alpha1 variant | |||
 ZZ | 2305 (62.16) | 51.89 (10.29) | 37.23 (9.96) |
 ZNull | 31 (0.84) | 52.11 (11.31) | 36.91 (9.64) |
 NullNull | 12 (0.32) | 53.17 (10.10) | 34.54 (9.99) |
 FF & FZ | 31 (0.84) | 50.80 (9.59) | 35.38 (9.88) |
 SZ | 382 (10.30) | 51.24 (10.53) | 36.50 (9.73) |
 MZ | 733 (19.77) | 50.43 (11.44) | 35.05 (9.42) |
 Otherc | 214 (5.77) | 50.19 (11.26) | 34.62 (9.80) |
Data available n=3708 | Â | Â | Â |