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Table 3 Laboratory and imaging findings of the study patients according to sex

From: Characteristics, treatments, in-hospital and long-term outcomes among inpatients with acute exacerbation of chronic obstructive pulmonary disease in China: sex differences in a large cohort study

Variable

Total

(N = 14,007)

Male (N = 11,020)

Female (N = 2987)

P Value

Laboratory tests

    

Hemoglobin (g/L)

127.28 ± 22.53

128.67 ± 22.54

122.16 ± 21.73

< 0.001

Anemia

3962(28.7)

3233(29.8)

729(24.7)

< 0.001

WBC(×109/L)

7.70(5.89–10.19)

7.78(6.00-10.27)

7.34(5.50–9.90)

< 0.001

WBC>10 × 109/L

3589(26.0)

2871(26.4)

718(24.3)

0.019

NEUT (%)

74.34 ± 12.76

74.38 ± 12.76

74.22 ± 12.77

0.570

EOSR (%)

1.0(0.1–2.6)

1.0(0.1–2.8)

0.7(0.1–2.2)

< 0.001

EOSR ≥ 2%

4490(32.7)

3694(34.3)

796(27.2)

< 0.001

Platelet (×109/L)

192(145–249)

194(146–251)

186(141-242.75)

< 0.001

Platelet < 100 × 109/L

1074(7.8)

817(7.5)

257(8.7)

0.031

PH

7.41(7.38–7.45)

7.41(7.38–7.45)

7.42(7.38–7.46)

< 0.001

PH < 7.30

350(3.9)

272(3.7)

78(4.5)

0.126

PaO2 (mmHg)

83.0(68.1–106.0)

83.35(68.80-106.10)

81.0(65.9–106.0)

0.207

PaCO2 (mmHg)

42.3(36.3–51.1)

42.2(36.3–50.70)

42.60(36.15–53.20)

0.077

ALT(U/L)

17(12–27)

18.00(12.00-27.70)

16(11–24)

0.336

AST(U/L)

22(17.4–29.3)

22.00(17.70-29.35)

22(17–29)

0.351

BUN (mmol/L)

5.70(4.30–7.61)

5.70(4.40–7.65)

5.40(4.00-7.56)

0.231

ALB(g/L)

36.8(33.4–40.0)

36.60(33.30–39.80)

37.40(33.90–40.80)

< 0.001

ALB < 35 g/L

4669(35.3)

3780(36.3)

889(31.8)

< 0.001

Creatinine (µmol/L)

75.65(61.0–96.0)

78.00(64.25-98.00)

65.00(53.00–86.00)

< 0.001

Increased creatinine

2628(19.3)

2098(19.6)

530(18.4)

0.148

NT-pro BNP (pg/ml)

320.00(103.00-1309.50)

283.00(91.91-1132.50)

55.35(169.00-2140.25)

0.994

cTNT (ng/L)

18.00(10.80–33.20)

18.60(11.10–34.50)

16.40(9.70–30.50)

0.104

D-dimer(mg/L)

0.73(0.40–1.54)

0.70(0.39–1.46)

0.87(0.48–1.82)

0.070

PCT (ng/ml)

0.12(0.05–0.43)

0.13(0.05–0.45)

0.10(0.05–0.37)

0.900

CRP (mg/L)

12.40(3.89–47.40)

12.90(3.84–51.40)

11.20(4.07–37.33)

< 0.001

CRP > 10 mg/L

4707(54.7)

3655(55.3)

1052(52.8)

0.052

Radiological findings

    

Pulmonary artery enlargement

265(1.9)

159(1.4)

106(3.5)

< 0.001

Pleural effusion

2619(18.7)

1993(18.1)

626(21.0)

< 0.001

Pulmonary bulla

3589(25.6)

3199(29.0)

390(13.1)

< 0.001

Atelectasis/consolidation

755(5.4)

537(4.9)

218(7.3)

< 0.001

Bronchiectasis

2021(14.4)

1421(12.9)

600(20.1)

< 0.001

Pulmonary interstitial fibrosis

963(6.9)

789(7.2)

174(5.8)

0.011

Right ventricular enlargement

125(0.9)

42(0.4)

16(0.5)

0.243

  1. Abbreviations WBC = white blood cell; NEUT = neutrophil ratio; EOSR = eosinophil ratio; ALT = alanine aminotransferase; AST = aspartate aminotransferase; BUN = blood urea nitrogen; ALB = albumin; NT-proBNP = N-terminal pro-B-type natriuretic peptide; cTNT = cardiac troponin T; PCT = procalcitonin; CRP = C-reactive protein