Table 2 Effects of PEEP on regional cerebral oxygen saturation, ventilatory and hemodynamic data in elderly patients

Primary outcome

rSO₂, mean ± SD, %

—

69 ± 9

67 ± 9

67 ± 8

0.002^b

Secondary outcomes

rSO₂, mean ± SD, %

75 ± 7

69 ± 9

67 ± 9

667 ± 8

<0.001^b

PaO₂^a,median(IQR),(mmHg)

—

112.0(80.6,184.6)

171.5(117.0,224.8)

163.0(109.3,303.3)

0.001

457.5(394.0,523.5)

<0.001

PaCO₂, mean ± SD, (mmHg)

—

39 ± 3

40 ± 4

41 ± 5

<0.001^c

39 ± 6

0.003^c

Ppeak, mean ± SD,(cmH₂O)

—

20 ± 2

21 ± 2

24 ± 2

<0.001

16 ± 2

<0.001

HR, mean ± SD, (beats/min)

—

68 ± 13

62 ± 10

62 ± 11

0.140^c

67 ± 11

0.156^c

MAP,median(IQR),(mmHg)

—

79.0(73.3,90.8)

82.67(76.5,91.5)

83.33(77.1,89.3)

0.442

84.5(76.4,95.0)

0.452

CI,median(IQR),(L/min∙m²)

—

2.15(1.83,2.40)

2.15(1.83,2.30)

2.10(1.93,2.28)

0.894

2.10(1.90,2.30)

0.961

SVV,median(IQR),%

—

9.00(5.00,10.00)

6.00(5.25,9.00)

7.00(5.25,9.00)

0.492

9.00(8.00,11.00)

0.004