Variables | Parentsa (n = 57) | Childrena (n = 55) | χ2 value |
p value |
---|
MP-DNA, n (%) | 14/17 (82.4) | 39/53 (73.6) | 0.167 | 0.683 |
MP-IgM, n (%) | 43/53 (81.1) | 42/51 (82.4) | 0.026 | 0.872 |
mNGS, n (%) | 12/13 (92.3) | 13/13 (100) | NA | 1.00 |
MRMP, n (%) | 3/5 (60) | 21/40 (52.5) | 0.00 | 1.00 |
Co-infection
| 13 (22.8) | 36 (65.5) | 20.687 |
< .001
|
Virusesb, n (%) | 10 (17.5) | 23 (41.8) | 7.936 |
0.005
|
Bacteriac, n (%) | 3 (5.3) | 20 (36.4) | 16.591 |
< .001
|
Fungusd, n (%) | 2 (3.5) | 3 (5.5) | 0.002 | 0.967 |
- Data are presented as number (%)
-
aAll % calculated for 57 or 55 patients, respectively, unless stated otherwise. In case % were calculated for less than the maximal number of patients, data for some patients were missing and the actual denominator is displayed
-
bFour adults tested positive for SARS-CoV-2 and three for parainfluenza virus. Other viral infections included respiratory syncytial virus, metapneumovirus, adenovirus, and rhinovirus, each affecting one adult. Parainfluenza virus infected ten children, rhinovirus seven, adenovirus five, Epstein-Barr virus three, influenza A virus one, and metapneumovirus one
-
cOne adult had Haemophilus influenzae, another had Pseudomonas holleri, and a third had Legionella pneumophila. Haemophilus influenzae affected fourteen children, Streptococcus pneumoniae seven, Staphylococcus aureus one, and Klebsiella pneumoniae one
-
dOne adult had Candida parapsilosis and another had Candida tropicalis. One child had Candida albicans, another had Candida parapsilosis, and a third had Aspergillus salviae
- Abbreviations NA Not available, MP-DNA
Mycoplasma pneumoniae DNA detection, MP-IgM
Mycoplasma pneumoniae IgM antibody detection, mNGS metagenomic next-generation sequencing detection, MRMP Macrolide-Resistant Mycoplasma pneumoniae