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Table 4 Pathogenic laboratory test results

From: Comparison of the clinical characteristics in parents and their children in a series of family clustered Mycoplasma pneumoniae infections

Variables

Parentsa (n = 57)

Childrena (n = 55)

χ2 value

p value

MP-DNA, n (%)

14/17 (82.4)

39/53 (73.6)

0.167

0.683

MP-IgM, n (%)

43/53 (81.1)

42/51 (82.4)

0.026

0.872

mNGS, n (%)

12/13 (92.3)

13/13 (100)

NA

1.00

MRMP, n (%)

3/5 (60)

21/40 (52.5)

0.00

1.00

Co-infection

13 (22.8)

36 (65.5)

20.687

 < .001

Virusesb, n (%)

10 (17.5)

23 (41.8)

7.936

0.005

Bacteriac, n (%)

3 (5.3)

20 (36.4)

16.591

 < .001

Fungusd, n (%)

2 (3.5)

3 (5.5)

0.002

0.967

  1. Data are presented as number (%)
  2. aAll % calculated for 57 or 55 patients, respectively, unless stated otherwise. In case % were calculated for less than the maximal number of patients, data for some patients were missing and the actual denominator is displayed
  3. bFour adults tested positive for SARS-CoV-2 and three for parainfluenza virus. Other viral infections included respiratory syncytial virus, metapneumovirus, adenovirus, and rhinovirus, each affecting one adult. Parainfluenza virus infected ten children, rhinovirus seven, adenovirus five, Epstein-Barr virus three, influenza A virus one, and metapneumovirus one
  4. cOne adult had Haemophilus influenzae, another had Pseudomonas holleri, and a third had Legionella pneumophila. Haemophilus influenzae affected fourteen children, Streptococcus pneumoniae seven, Staphylococcus aureus one, and Klebsiella pneumoniae one
  5. dOne adult had Candida parapsilosis and another had Candida tropicalis. One child had Candida albicans, another had Candida parapsilosis, and a third had Aspergillus salviae
  6. Abbreviations NA Not available, MP-DNA Mycoplasma pneumoniae DNA detection, MP-IgM Mycoplasma pneumoniae IgM antibody detection, mNGS metagenomic next-generation sequencing detection, MRMP Macrolide-Resistant Mycoplasma pneumoniae