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Table 2 Laboratory results

From: Comparison of the clinical characteristics in parents and their children in a series of family clustered Mycoplasma pneumoniae infections

Variablesa

Parents groupb (n = 57)

Children groupb (n = 55)

χ2 value

p value

WBC (× 109 per L; normal range for adults 3.5–9.5; for children 4–10.5)

6.9 ± 2.1

8.6 ± 3.3

  

Increased, n (%)

7/56 (12.5)

10/54 (18.5)

0.762

0.383

Decreased, n (%)

0/56 (0)

2/54 (3.7)

0.547

0.459

Neu (× 109 per L; normal range for adults 1.8–6.3; for children 1.08–5.8)

4.4 ± 1.8

4.9 ± 2.4

  

Increased, n (%)

9/56 (16.1)

12/52 (23.1)

0.845

0.358

Lym (× 109 per L; normal range for adults 1.1–3.2; for children 1.15–6)

1.7 ± 0.8

2.9 ± 1.6

  

Increased, n (%)

2/56 (3.6)

6/52 (11.5)

1.469

0.226

Decreased, n (%)

14/56 (25)

1/52 (1.9)

12.006

0.001

Hb (g/L; normal range for adults 115–150; for children 110–149)

129 ± 14

124 ± 12

  

Decreased, n (%)

6/56 (10.7)

7/54 (13.0)

0.133

0.715

PLT (× 109 per L; normal range for adults 125–350; for children 100–378)

263 ± 64

310 ± 104

  

Increased, n (%)

6/56 (10.7)

20/54 (37.0)

10.553

0.001

Decreased, n (%)

0/56 (0)

0/54 (0)

  

CRP (mg/L; normal range < 3)

21.7 ± 27.6

15.1 ± 19.9

  

Increased, n (%)

44/56 (78.6)

40 (72.7)

0.515

0.473

PCT (ng/mL; normal range 0–0.05)

0.05 ± 0.02

0.18 ± 0.32

  

Increased, n (%)

7/52 (13.5)

40/52 (76.9)

42.275

 < .001

ESR (mm/h; normal range 0–26)

40 ± 24

29 ± 18

  

Increased, n (%)

33/45 (73.3)

7/11 (63.6)

0.071

0.790

PT (s; normal range 9–13)

12.2 ± 1.1

10.8 ± 0.8

  

Increased, n (%)

11/55 (20)

0/16 (0)

2.413

0.120

D-dimer (mg/L; normal range for adults 0–0.55; for children 0–0.5)

0.42 ± 0.35

0.53 ± 0.35

  

Increased, n (%)

9/56 (16.1)

6/17 (35.3)

1.892

0.169

ALT (U/L; normal range for adults 7–40; for children 9–50)

28 ± 35

18 ± 17

  

Increased, n (%)

9/56 (16.1)

2 (3.6)

4.806

0.028

AST (U/L; normal range for adults 13–35; for children 15–40)

23 ± 16

32 ± 13

  

Increased, n (%)

4/56 (7.1)

12 (21.8)

4.844

0.028

ALP (U/L; normal range for adults 35–100; for children 45–125)

68 ± 24

171 ± 53

  

Increased, n (%)

4/56 (7.1)

21/54 (38.9)

15.776

 < .001

ALB (g/L; normal range 40–55)

41.8 ± 3.4

43.1 ± 2.5

  

Decreased, n (%)

18 (31.6)

6/54 (11.1)

6.855

0.009

TBIL (umol/L; normal range 0–23)

12.7 ± 15.9

5.6 ± 1.9

  

Increased, n (%)

4 (7.0)

0/54 (0)

2.171

0.141

DBIL (umol/L; normal range 0–8)

5.2 ± 10.1

1.9 ± 0.7

  

Increased, n (%)

3 (5.3)

0/54 (0)

1.262

0.261

BUN (mmol/L; normal range for adults 2.6–7.5; for children 3.1–8)

3.9 ± 1.2

3.6 ± 1.1

  

Increased, n (%)

0 (0)

0/54 (0)

NA

NA

Cr (umol/L; normal range for adults 41–73; for children 57–97)

59 ± 14

31 ± 11

  

Increased, n (%)

3 (5.3)

0 (0)

1.298

0.255

CK (U/L; normal range for adults 40–200; for children 50–310)

86 ± 56

108 ± 115

  

Increased, n (%)

1/14 (7.1)

2/51 (3.9)

NA

0.523

LDH (U/L; normal range 120–250)

208 ± 37

319 ± 67

  

Increased, n (%)

6/53 (11.3)

42/54 (77.8)

47.758

 < .001

  1. Data are presented as means ± SD or number (%)
  2. aNo t-test was performed to compare the two groups of children and adults, as the normal ranges of laboratory tests were different for the two groups
  3. bAll % calculated for 57 or 55 patients, respectively, unless stated otherwise. In case % were calculated for less than the maximal number of patients, data for some patients were missing and the actual denominator is displayed
  4. Abbreviations NA Not available, WBC White blood cell, Neu Neutrophil, Lym Lymphocyte, Hb Hemoglobin, PLT Platelet, CPR C-reactive protein, PCT Procalcitonin, ESR Erythrocyte sedimentation rate, PT Prothrombin time, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, ALB Albumin, TBIL Total bilirubin, DBIL Direct bilirubin, BUN Blood urea nitrogen, Cr Creatinine, CK Creatine kinase, LDH Lactate dehydrogenase