Table 1 Characteristics of patients with PTB and matched controls
| Â | Cases (n = 4265) | Controls (n = 17,060) | *p-Value |
|---|---|---|---|
Age at enrollment, years | Â | Â | 0.934 |
Median (IQR) | 46 (27, 62) | 46 (27, 62) | Â |
Sex, n (%) | Â | Â | 1.000 |
Female | 1567 (36.74) | 6268 (36.74) | Â |
Male | 2698 (63.26) | 10,792 (63.26) | Â |
Place of residence, n (%) | Â | Â | 1.000 |
Rural | 1607 (37.68) | 6426 (37.67) | Â |
Urban | 2658 (62.32) | 10,634 (62.33) | Â |
Southern Shandong †| 1192 (27.95) | 4772 (27.97) |  |
Northern Shandong ‡ | 976 (22.88) | 3902 (22.87) |  |
Central Shandong § | 1009 (23.66) | 4034 (23.65) |  |
Jiaodong Peninsula ¶ | 1088 (25.51) | 4352 (25.51) |  |
Enrollment year, n (%) | Â | Â | 1.000 |
2013 | 3555 (83.35) | 14,220 (83.35) | Â |
2014 | 340 (7.97) | 1360 (7.97) | Â |
2015 | 266 (6.24) | 1062 (6.23) | Â |
2016 | 79 (1.85) | 318 (1.86) | Â |
2017 | 25 (0.59) | 100 (0.59) | Â |
Time from entry to index date, years | Â | Â | 0.100 |
Median (IQR) | 2.54 (1.26, 3.68) | 2.58 (1.30, 3.72) | Â |
Number of comorbidities, n (%) | Â | Â | < 0.001 |
None | 2741 (64.26) | 14,409 (84.46) | Â |
1 | 675 (15.83) | 1510 (8.85) | Â |
2 | 351 (8.23) | 600 (3.52) | Â |
≥ 3 | 498 (11.68) | 541 (3.17) |  |
CCI score | Â | Â | < 0.001 |
Low, CCI = 0 | 3184 (74.66) | 15,695 (92.00) | Â |
Moderate, CCI = 1–2 | 871 (20.42) | 1149 (6.73) |  |
High, CCI > 2 | 210 (4.92) | 216 (1.27) | Â |