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Table 8 Follow-up data of borderline PH, according to definition of PVR cut-off ≥ 3 WU

From: Characteristics of patients meeting the new definition of pre-capillary pulmonary hypertension (Nice 2018) in a single Japanese pulmonary hypertension center

Group

Group of PH

Background disease

Age at diagnosis

RHC at diagnosis

Desition after first RHC

RHC at final follow up

Desition after final RHC

Outcome

mPAP

(mmHg)

PVR

(WU)

PCWP

(mmHg)

mPAP

(mmHg)

PVR

(WU)

PCWP

(mmHg)

Boderline PH

1

SSc

37

22

2.6

5

Follow up

37

2.6

9

Ambrisentan

Deceased because of lung cancer in 14 month

Boderline PH

3

COPD

65

23

2.6

5

Follow up

35

3.7

4

Treatment of COPD

Became feasible because of COPD

Boderline PH

3

SSc + Fibrosis

35

20

1.2

11

Follow up

40

2.9

16

Treatment of left heart failure

Deceased because of left heart failure in 11 month

Boderline PH

4

CTEPH

46

24

2.4

7

Follow up

19

1.1

10

Follow up

Stable

Boderline pre-capillary PH

4

Aortitis

61

24

5.8

4

Follow up

29

7.7

1

Riociguat

Improved after the treatment of riociguat

  1. SSc, Systemic sclerosis; COPD, Chronic obstructive pulmonary disease; CTEPH; Chronic thromboembolic pulmonary hypertension