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Table 2 mMRC, CAT and SGRQ-c scores of COPD patients according to their COPD phenotypes

From: Clinical phenotypes and heath-related quality of life of COPD patients in a rural setting in Malaysia – a cross-sectional study

Quality of Life Measurement

Clinical Phenotype, n (%)

NON-AE

108 (58.4)

ACO

26 (14.1)

AE

51 (27.6)

p-value

mMRC, n, (%)

 0–1

90 (83.3)

16 (61.5)

16 (31.4)

<  0.001

 2–4

18 (16.7)

10 (38.5)

35 (68.6)

 

CAT, score (mean ± SD, 95% CI)

 Total

5.5 ± 4.7;

11.7 ± 8.6;

17.3 ± 9.5;

<  0.001

4.6–6.4

8.2–15.2

14.6–19.9

 Cough

1.9 ± 1.3;

2.6 ± 1.1;

3.2 ± 1.5;

<  0.001

1.7–2.2

2.2–3.1

2.8–3.6

 Mucus

1.3 ± 1.2;

1.9 ± 1.5;

2.5 ± 1.6;

<  0.001

1.0–1.5

1.3–2.5

2.1–3.0

 Chest tightness

0.4 ± 0.7;

1.4 ± 1.4;

2.2 ± 1.4;

<  0.001

0.3–0.5

0.9–2.0

1.9–2.6

 Walk uphill

0.9 ± 1.1;

1.8 ± 1.3;

2.7 ± 1.5;

< 0.001

0.7–1.1

1.3–2.3

2.3–3.1

 Home activity

0.3 ± 0.7;

1.2 ± 1.5;

2.0 ± 1.6;

< 0.001

0.2–0.5

0.6–1.8

1.5–2.4

 Leaving home

0.2 ± 0.6;

0.9 ± 1.1;

1.7 ± 1.5;

< 0.001

0.1–0.3

0.4–1.3

1.2–2.1

 Sleep

0.2 ± 0.6;

0.9 ± 1.2;

1.2 ± 1.2;

< 0.001

0.1–0.3

0.4–1.4

0.9–1.6

 Energy

0.3 ± 0.6;

1.0 ± 1.4;

1.8 ± 1.5;

< 0.001

0.2–0.4

0.5–1.6

1.3–2.2

SGRQ-c, % (mean ± SD, 95% CI)

 Total

16.4 ± 14.8;

34.4 ± 19.5;

53.5 ± 22.7;

< 0.001

13.5–19.2

26.5–42.2

47.1–59.8

 Symptoms

18.3 ± 14.3;

41.9 ± 16.1;

64.6 ±20.2;

< 0.001

15.5–21.0

35.4–48.4

58.9 − 70.3

 Activities

27.1 ± 23.2;

36.3 ± 19.4;

57.8 ± 20.9;

< 0.001

22.6–31.5

28.4–44.1

52.0–63.7

 Impact

9.3 ± 14.3;

30.6 ± 26.1;

47.1 ± 29.9;

< 0.001

6.6–12.1

20.0–41.2

38.7–55.5

  1. Abbreviation: COPD chronic obstructive pulmonary disease, NON-AE non-exacerbators, ACO asthma-COPD overlap, AE frequent exacerbators, mMRC modified Medical Research Council, CAT COPD Assessment Test, SGRQ-c St George’s Respiratory Questionnaire for COPD, SD standard deviation; 95% CI, 95% confidence interval
  2. p-values with bold are significant