Quality of Life Measurement | Clinical Phenotype, n (%) | |||
---|---|---|---|---|
NON-AE 108 (58.4) | ACO 26 (14.1) | AE 51 (27.6) | p-value | |
mMRC, n, (%) | ||||
0–1 | 90 (83.3) | 16 (61.5) | 16 (31.4) | < 0.001 |
2–4 | 18 (16.7) | 10 (38.5) | 35 (68.6) | |
CAT, score (mean ± SD, 95% CI) | ||||
Total | 5.5 ± 4.7; | 11.7 ± 8.6; | 17.3 ± 9.5; | < 0.001 |
4.6–6.4 | 8.2–15.2 | 14.6–19.9 | ||
Cough | 1.9 ± 1.3; | 2.6 ± 1.1; | 3.2 ± 1.5; | < 0.001 |
1.7–2.2 | 2.2–3.1 | 2.8–3.6 | ||
Mucus | 1.3 ± 1.2; | 1.9 ± 1.5; | 2.5 ± 1.6; | < 0.001 |
1.0–1.5 | 1.3–2.5 | 2.1–3.0 | ||
Chest tightness | 0.4 ± 0.7; | 1.4 ± 1.4; | 2.2 ± 1.4; | < 0.001 |
0.3–0.5 | 0.9–2.0 | 1.9–2.6 | ||
Walk uphill | 0.9 ± 1.1; | 1.8 ± 1.3; | 2.7 ± 1.5; | < 0.001 |
0.7–1.1 | 1.3–2.3 | 2.3–3.1 | ||
Home activity | 0.3 ± 0.7; | 1.2 ± 1.5; | 2.0 ± 1.6; | < 0.001 |
0.2–0.5 | 0.6–1.8 | 1.5–2.4 | ||
Leaving home | 0.2 ± 0.6; | 0.9 ± 1.1; | 1.7 ± 1.5; | < 0.001 |
0.1–0.3 | 0.4–1.3 | 1.2–2.1 | ||
Sleep | 0.2 ± 0.6; | 0.9 ± 1.2; | 1.2 ± 1.2; | < 0.001 |
0.1–0.3 | 0.4–1.4 | 0.9–1.6 | ||
Energy | 0.3 ± 0.6; | 1.0 ± 1.4; | 1.8 ± 1.5; | < 0.001 |
0.2–0.4 | 0.5–1.6 | 1.3–2.2 | ||
SGRQ-c, % (mean ± SD, 95% CI) | ||||
Total | 16.4 ± 14.8; | 34.4 ± 19.5; | 53.5 ± 22.7; | < 0.001 |
13.5–19.2 | 26.5–42.2 | 47.1–59.8 | ||
Symptoms | 18.3 ± 14.3; | 41.9 ± 16.1; | 64.6 ±20.2; | < 0.001 |
15.5–21.0 | 35.4–48.4 | 58.9 − 70.3 | ||
Activities | 27.1 ± 23.2; | 36.3 ± 19.4; | 57.8 ± 20.9; | < 0.001 |
22.6–31.5 | 28.4–44.1 | 52.0–63.7 | ||
Impact | 9.3 ± 14.3; | 30.6 ± 26.1; | 47.1 ± 29.9; | < 0.001 |
6.6–12.1 | 20.0–41.2 | 38.7–55.5 |