The global impact of Aspergillus infection on COPD

Hammond, Emily E.; McDonald, Charles S.; Vestbo, Jørgen; Denning, David W.

doi:10.1186/s12890-020-01259-8

BMC Pulmonary Medicine

Table 5 Hospitalisation data by country collated from our systematic literature review. The BREATHE study [18, 42] and Foo et al [59] documented the incidence of hospitalisations per patient, whereas other studies [45, 63] do not clarify whether the figures reflect total number of hospitalisations annually (a patient can have multiple exacerbations a year requiring admission, dependent on their stage of disease), or per patient. A conservative estimate of 10.5%, based on the BREATHE study’s figure for Algeria was used to calculate average hospitalisation rates for all countries

From: The global impact of Aspergillus infection on COPD

	Country	Study	Study size	COPD annual hospitalisation rate
Africa	Northern Africa
	Algeria	BREATHE study, 2012 [18, 42]	3,675	10.50%
	Egypt	BREATHE study, 2012 [18, 42]	9,804	20.30%
	Morocco	BREATHE study, 2012 [18, 42]	3,983	13.00%
	Tunisia	BREATHE study, 2012 [18, 42]	1,952	11.30%
Americas	Latin American and the Caribbean
	Brazil	Foo et al, 2016 [59]	300	20.00%
	Colombia	Alvarez-Moreno et al, 2018 [60]	Population	13.99%
	Mexico	Foo et al, 2016 [59]	328	14.00%
	Trinidad and Tobago	Gugnani and Denning, 2015 [61]	Population	13.00%
	Northern America
	United States of America	Foo et al, 2016 [59]	1,001	12.00%
Asia	Eastern Asia
	China	Zhu et al, 2018 [45]	155,777	20.87%
	Japan	Foo et al, 2016 [59]	300	3.00%
	Korea (Republic of)	Foo et al, 2016 [59]	300	5.00%
	South-Eastern Asia
	Thailand	Chayakulkeeree et al, 2017 [62]	731,450	7.00%
	Southern Asia
	Pakistan	BREATHE study, 2012 [18, 42]	3,654	13.00%
	Western Asia
	Jordan	BREATHE study, 2012 [18, 42]	3,596	20.70%
	Lebanon	BREATHE study, 2012 [18, 42]	3,417	28.80%
	Saudi Arabia	BREATHE study, 2012 [18, 42]	9,675	22.20%
	Syrian Arab Republic	BREATHE study, 2012 [18, 42]	3,402	21.90%
	Turkey	BREATHE study, 2012 [18, 42]	14,911	19.30%
	United Arab Emirates	BREATHE study, 2012 [18, 42]	3,482	40.70%
Europe	Eastern Europe
	Romania	Mares et al, 2018 [63]	Population	22.07%
	Russian Federation	Foo et al, 2016 [59]	301	14.00%
	Northern Europe
	United Kingdom and N. Ireland	Foo et al, 2016 [59]	305	15.00%
	Southern Europe
	Greece	Gamaletsou et al, 2016 [64]	Population	7.70%
	Italy	Foo et al, 2016 [59]	302	6.00%
	Spain	Foo et al, 2016 [59]	303	16.00%
	Western Europe
	France	Foo et al, 2016 [59]	300	8.00%
	Germany	Foo et al, 2016 [59]	300	9.00%
	Netherlands	Foo et al, 2016 [59]	303	7.00%

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ISSN: 1471-2466

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