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Table 3 Compared patient data in the “eradication” and “persistence” groups. Results are expressed in numbers or mean ± standard deviation

From: Management of initial colonisations with Burkholderia species in France, with retrospective analysis in five cystic fibrosis Centres: a pilot study

Patient data

Eradication (N = 10)

Persistence (N = 7)

p value

Male

8

5

1

Age at PC (years)

19.1 ± 8.6

20.2 ± 8.0

0.74

BMI (Z-score) at PC

−1.04 ± 0.8

−0.62 ± 0.6

0.42

Antibiotics in the 3 months before PC

9

3

0.1

Lung function (% predicted)

 FVC at PC

92.8 ± 15.6

65.3 ± 20.1

0.11

 FEV1 at PC

85.4 ± 27.4

65.7 ± 23.0

0.12

 FEV1 2 years after PCa

77.7 ± 26.1

57.2 ± 18.4

0.08

Distribution ofBurkholderiastrains at PC

BCC

8

6

 

B. multivorans

3

3

0.64

B. cenocepacia

2

2

1

B. contaminans

1

0

1

B. vietnamiensis

1

0

1

B. ambifaria

0

1

0.41

 Unidentified BCC

1

0

1

B. gladioli

2

1

1

Antibiotic treatment

 No treatment

4

2

1

 Eradication treatment

6

5

1

 Time to treat from the PC (days)

34 ± 20.5

48 ± 37.9

0.71

Consistency antibiogram/antibiotic therapy

 Consistentb

5

1

0.08

 Inconsistent

1

4

 
  1. BMI Body Mass Index, PC primary colonisation, FVC Forced Vital Capacity, FEV1 Forced Expiratory Volume in one second, BCC Burkholderia cepacia complex
  2. a Data unavailable for one patient with one-year follow-up,
  3. b in vitro full susceptibility to at least two of the antibiotics used, or to at least one antibiotic if combined with inhaled tobramycin