Table 1 Studies in idiopathic pulmonary fibrosis utilizing Gender-Age-Physiology (GAP) index and Composite physiologic index (CPI) in their study protocols

[5]

Comparison of GAP and CPI

CPI and GAP were predictive of 1-, 2- and 3-year mortality

[6]

FVC > 80% in comparison with GAP I and CPI ≤40

CPI and GAP significantly predicted disease progression and 1-, 2- and 3-year mortality. Higher scores in GAP (>I) and CPI (> 40) predicted poorer survival.

[7]

Clinical characteristics according to GAP stage

Significant CPI and survival differences between GAP stages

[8]

GAP and CPI in different smoking status groups

CPI was higher in never-smokers. GAP predicted AEx in never-smokers. GAP was strong predictor of mortality in never-smoking patients

[9]

Risk factors of AEx-IPF

GAP and CPI did not differ significantly between AEx and non-AEX groups. GAP stage ≥II was related to survival and risk for AEx. GAP stage ≥ II predicted AEx

[10]

CPI, GAP, DSP and duBois score in survival prediction

All the indexes were predictive for survival, CPI being the most accurate.

[11]

Stratification for CT algorithm and GAP/CPI

CPI estimated severity of ILD better than GAP. CPI was more accurate mortality predictor than GAP. Mortality prediction was improved compared to GAP when stratification was based on CT algorithm and CPI.

[12]

CPI and GAP in mortality prediction during lung transplant assessment

Higher CPI and GAP were associated with mortality

[13]

GAP and CPI in severity assessment in different HRCT patterns

CPI, but not GAP differentiated significantly between the groups