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Table 3 Demographics of the 34 subjects recruited with endobronchial biopsy for CC16 immunostaining performed

From: CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers

 

Non-smokers

(n = 10)

Ex-smokers

(n = 11)

Chronic smokers

(n = 13)

Men*

3 (30%)

11 (100%)

13 (100%)

Age (years)

56.3 ± 14.7

63 ± 9.5

67.4 ± 7.1

FEV1

(Liters, % pred)

2.2 ± 0.6 L,

102.3 ± 2.8%

2.4 ± 0.5 L,

97.5 ± 6.5%

2.1 ± 0.3 L,

89.1 ± 5.2%

FVC

(Liters, % pred)

2.9 ± 0.6 L,

113.4 ± 4.6%

3.6 ± 0.5 L,

106.0 ± 5.3%

3.4 ± 0.5 L,

92.3 ± 7.2%

FEV1/FVC (%)

73.6 ± 11.8

66.6 ± 12.5

62.9 ± 10.8

CC16 intensity

 

0

2 (20%)

3 (27%)

5 (39%)

 

1

3 (30%)

4 (36%)

3 (23%)

 

2

5 (50%)

4 (36%)

5 (39%)

  1. Significance testing used analysis of variance for continuous variables and chi-square for categorical variables. * p < 0.001. FEV1 = forced expiratory volume in 1 s. FVC = forced vital capacity. CC16 = Club cell protein-16