Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12890-018-0591-y/MediaObjects/12890_2018_591_Fig4_HTML.gif)
HRCT and surgical lung biopsy of 58-year-old never-smoking woman. a Computed tomography scan shows traction bronchiectasis, reticulation, and ground-glass opacity predominantly in the peribronchovascular zone of both lower lungs. b Pathologic specimen (H & E staining, × 40) shows fibrotic nonspecific interstitial pneumonia with emphysematous change (grade 2). c Muscular pulmonary artery shows medial hypertrophy (grade 1) (Elastica van Gieson staining, × 100). d Pulmonary venule lying along the alveolar ducts shows no apparent intimal thickening (Elastica van Gieson staining, × 200). e Venule and interlobular vein show intimal thickening (Elastica van Gieson staining, × 200)