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Table 2 Pulmonary function tests of patients with and without emphysema.

From: Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

 

Emphysema (E)

Non-emphysema Smokers (S)

Non-emphysema Non-Smokers (NS)

Between groups differences

n

17

8

10

 

FEV1 % predicted value (% pred)

41.7 ± 26.6 *,†

71 ± 21.3

82 ± 11.1

p < 0.001

FEV1/FVC

48.7 ± 13.9 *,†

67.6 ± 14.8†

86.9 ± 11.6

p < 0.001

RV (%pred)

211.6 ± 69.4 *,†

123 ± 19.7

88 ± 23.9

p < 0.001

TLC (%pred)

121.5 ± 17.8 *,†

100 ± 10.4 †

83 ± 13.5

p < 0.001

PaO2 (mmHg)

69.7 ± 10.1 *,†

81 ± 15.8

85.2 ± 7.6

p < 0.005

PaCO2 (mmHg)

41.3 ± 5

38.7 ± 7.7

41.8 ± 2.6

ns

  1. *: vs S, p < 0.01; †: vs NS, p < 0.01; as assessed by Mann-Whitney U-test. ns: non significant
  2. PaO2: arterial oxygen pressure, PaCO2: arterial carbon dioxide pressure, FEV1: forced expiratory volume in one second, RV: residual volume, FVC: forced vital capacity, TLC: total lung capacity.